Advanced Practice in Critical Care provides experienced critical care nurses with a clear and distinct evidence base for contemporary critical care practice. Central to the book is the application of research and evidence to practice and therefore, case studies and key critical care clinical situations are used throughout to guide the reader through the patient care trajectory. ? Each chapter introduces an initial patient scenario and as the chapter progresses, the patient scenario develops with the theoretical perspectives and application. In this way, it is evident how multi-organ dysfunction develops, impacting upon and influencing other body systems, demonstrating the multi-organ impact that is often experienced by the critically ill patient. In this way, consequences of critical illness such as acute renal failure, haemostatic failure and liver dysfunction are explored.