Completely updated, the Fifth Edition of this standard-setting two-volume reference presents the most advanced diagnostic techniques and the latest information on all currently known disease entities. More than 90 preeminent surgical pathologists offer expert advice on the diagnostic evaluation of every type of specimen from every anatomic site. The Fifth Edition contains over 4,400 full-color photographs. This edition provides detailed coverage of the latest developments in the field, including new molecular and immunohistochemical markers for diagnosis and prognosis of neoplasia, improved classification systems for diagnosis and prognosis, the role of pathology in new diagnostic and therapeutic techniques, and the recognition of new entities or variants of entities. All full-color illustrations have been color-balanced to dramatically improve image quality.