Co-published with the New England Journal of Medicine, the first two editions of Medical Uses of Statistics have been widely praised for providing a basic understanding of statistical concepts, methods, and techniques in health-related areas of study. Now in a Third Edition, this book continues to present both the fundamental techniques and the state-of- the-art information for a modern and accessible understanding of statistical applications in the fields of medicine, biostatistics, and clinical research. The editors have updated this new edition with more than 50% new material on recent developments, applicable methods, and best practices. Self-contained chapters that readers can work with independently of one another are organized into five succinct sections that cover basic statistical concepts, the design of medical investigations, data analysis, reporting results, and a concluding discussion of specialized topics in medical literature. This book surveys statistical applications now used in clinical research and illustrates good and poor uses of methods, and it also features numerous new chapters on clinical trials, statistical methods in epidemilogy studies, and statistics in genetics.  New topical coverage includes linear regression, categorical data analysis, meta-analysis, subgroup analysis, and risk analysis The book's numerous examples are taken straight from the pages of the New England Journal of Medicine, ensuring a relevant and modern presentation.