This Laboratory Manual accompanies the first and second editions of Marian K. Kazimierczuks Pulse-Width Modulated DC-DC Power Converters (Wiley). It covers most of the design aspects of the key power electronic converters, making it highly beneficial to students, researchers, instructors and industrial engineers. The main objective of a laboratory is to develop software simulation skills in the area of power electronics and to enhance the understanding of power converters. Based on this, at least two laboratory exercises will be provided for every chapter of Pulse-Width Modulated DC-DC Power Converters. Selected laboratory topics can be used depending on the course structure and can be taught in one semester or over a span of two or even three semesters. There will be more labs than the number of weeks in two semesters to make the syllabus as flexible as possible. The Laboratory Manual will constitute of three parts, namely Part A, Part B, and Part C. The exercises in Part A will emphasize the open-loop analysis of the power stages of pulse-width modulated (PWM) buck, boost, buck-boost, flyback, forward, half-bridge and full-bridge DC-DC power converters in continuous conduction mode (CCM) and discontinuous conduction mode (DCM). Part B will present MATLAB and simulations relevant to small-signal modelling and dynamic analysis of closed-loop boost DC-DC power converters. The topics in Part C will discuss the physical properties of the Silicon (Si), Silicon Carbide (SiC), and Gallium Nitride (GaN) semiconductor devices and design of semiconductor devices used in pulse-width modulated DC-DC converters. The manuals laboratory exercises have been taught and continuously improved for over 25 years by Marian K. Kazimierczuk thanks to constructive student feedback and valuable suggestions on possible laboratory improvements. Presenting the most updated and highly informative teaching material for the benefit of a wide variety of audience is the purpose of this work.